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Hair Loss Treatment For Women In Midlife & Menopause

Metro Health and Wellness LLC

Kirstie Cunningham, MD, FACOG, NCMP

OB-GYN located in Marietta, GA & Nashville, TN

Hair thinning during midlife is common—but it is not something you have to accept. Hormonal changes, aging, inflammation, and genetics can disrupt the hair growth cycle, leading to increased shedding, reduced density, and loss of volume over time. Our hair loss treatments for women are designed to address these changes at the cellular level using advanced regenerative therapies. Through personalized PRP hair restoration and cutting-edge exosome hair therapy, we help restore scalp health, reactivate dormant follicles, and support naturally fuller, healthier hair.

Advanced PRP and Exosome Hair Restoration for Thinning Hair

Hair Loss Treatment for Women

Advanced Regenerative Hair Restoration for Midlife & Menopause

Hair thinning and hair loss are common concerns for women during perimenopause and menopause. Hormonal changes, genetics, inflammation, stress, and aging can disrupt the hair growth cycle—leading to increased shedding, widening parts, reduced density, and slower regrowth.

We offer advanced, non-surgical hair loss treatments for women that address thinning hair at the cellular level. Using regenerative therapies such as PRP hair restoration and exosome hair therapy, we create personalized treatment plans designed to restore scalp health and support fuller, healthier hair over time.

Understanding Hair Loss in Midlife Women

Hair follicles cycle through four phases:
Anagen (growth), Catagen (transition), Telogen (rest), and Exogen (shedding).

Healthy hair spends most of its life in the anagen (growth) phase. During midlife, declining estrogen levels, reduced blood flow, inflammation, and altered cellular signaling can cause follicles to spend less time growing and more time resting or shedding. Over time, this leads to visible thinning and decreased volume.

Modern hair restoration focuses on cellular signaling pathways—the biological messages that tell hair follicles when to grow, regenerate, or shed.

PRP Hair Loss Treatment

Platelet-Rich Plasma (PRP) for Thinning Hair

PRP hair restoration uses your body’s own regenerative capacity to support hair growth. A small amount of blood is drawn and processed to concentrate platelets, which contain a complex mixture of growth factors and bioactive proteins.

How PRP Works for Hair Loss

The exact mechanism of PRP is not fully understood, but PRP contains at least six known growth factors and more than 30 additional biologically active substances—including chemokines, clotting factors, and immune mediators—that may influence hair growth individually and synergistically.

Key growth factors involved in hair restoration include:

  • Fibroblast Growth Factor (FGF) – supports follicle health

  • Vascular Endothelial Growth Factor (VEGF) – improves blood supply to follicles

  • Epidermal Growth Factor (EGF) – supports follicular regeneration

Together, these growth factors may:

  • Prolong the anagen (growth) phase

  • Increase hair shaft thickness

  • Improve scalp circulation

  • Reduce excessive shedding

Who Is a Good Candidate for PRP Hair Restoration?

PRP is best suited for women who:

  • Have thinning hair rather than complete baldness

  • Are experiencing early or more recent hair loss

  • Have diffuse thinning at the crown or part

  • Prefer a natural, autologous treatment approach

Because PRP relies on platelet concentration, individuals with higher baseline platelet levels may experience more robust results.

The PRP Treatment Process

  • Consultation and informed consent

  • Blood draw and processing to concentrate platelets (typically 2–6× baseline levels)

  • Scalp injections using small, precise volumes

  • PRP is often combined with microneedling to enhance growth factor release

  • Local anesthetic or comfort measures may be used

PRP Treatment Schedule & Maintenance

PRP is not a one-time treatment. A common protocol includes:

  • One session monthly for three months

  • Maintenance or booster sessions every six months

Your treatment plan is individualized based on hair loss pattern, response, and goals.

PRP Results, Safety & Considerations

PRP may result in:

  • Decreased shedding

  • Thicker-appearing hair

  • Improved density over time

Results vary, and benefits are maintained only with ongoing treatment. PRP is considered very safe since it uses your own blood. Temporary scalp tenderness is the most common side effect.

Exosome Hair Therapy

Advanced Regenerative Treatment for Hormone-Related Hair Loss

For many women, especially during menopause, hair loss is driven by impaired cellular communication and inflammation, not just reduced blood flow. This is where exosome hair therapy offers an advanced solution.

AnteAGE MDX® Exosome Hair Solution

AnteAGE MDX® Exosome Hair Therapy represents the next generation of non-surgical hair restoration.

Exosomes are microscopic, cell-derived signaling vesicles that deliver targeted biological instructions to hair follicles—without introducing live stem cells.

The Science Behind Exosome Hair Restoration

AnteAGE MDX uses a proprietary stem cell culture process to produce exosomes optimized to:

  • Upregulate Wnt/β-catenin signaling, a critical pathway for hair follicle development and regeneration

  • Support cellular communication within the scalp

  • Modulate inflammatory pathways such as JAK-STAT, which can disrupt hair growth

The formulation also includes:

  • Caffeine to stimulate follicles and enhance circulation

  • Azelaic acid to help counteract the effects of DHT, a hormone associated with follicle miniaturization

This multi-pathway approach makes exosome therapy particularly effective for menopause-related and hormone-driven hair loss.

Expected Results with Exosome Hair Therapy

Patients may experience:

  • Reduced shedding within the first few months

  • Improved hair density and thickness over time

  • Healthier scalp environment supporting long-term hair growth

Exosome therapy may be performed alone or combined with PRP for enhanced regenerative results.

PRP vs Exosomes for Hair Loss

PRP and exosome therapy work through different but complementary mechanisms. PRP delivers growth factors from your own blood, while exosomes deliver targeted cellular signals that activate hair growth pathways.

Many midlife women benefit most from a combined PRP + exosome approach, particularly when hair loss is multifactorial.

Who Is a Candidate for Hair Loss Treatment?

You may be a good candidate if you are experiencing:

  • Thinning hair during perimenopause or menopause

  • Increased shedding or reduced density

  • Widening part or crown thinning

  • Hormone-related or age-related hair loss

A Personalized Approach to Hair Restoration

Hair loss treatment is never one-size-fits-all. During your consultation, we assess:

  • Hair loss pattern and severity

  • Hormonal and menopausal status

  • Scalp health and inflammation

  • Prior treatments and goals

This allows us to design a custom hair restoration plan that supports confidence, volume, and scalp health—now and long term.

Schedule a Hair Restoration Consultation

Discover refined, science-backed solutions for thinning hair designed specifically for women in midlife.